HyloPReP™ – HA + LP-PRP Hybrid System for OA Repair
HyloPReP™ – HA + LP-PRP Hybrid System for OA Repair
HyloPReP™ – HA + LP-PRP Hybrid System for OA Repair
HyloPReP™ is our “first-of-its-kind” combination integrating Leukocyte Poor-PRP LP- PRP kit and Hyaluronic Acid (HA) for targeted osteoarthritis (OA) management
HyloPReP™ is our “first-of-its-kind” combination integrating Leukocyte Poor-PRP LP- PRP kit and Hyaluronic Acid (HA) for targeted osteoarthritis (OA) management
HyloPReP™ is our “first-of-its-kind” combination integrating Leukocyte Poor-PRP LP- PRP kit and Hyaluronic Acid (HA) for targeted osteoarthritis (OA) management
Synergistic Healing: HA Meets PRP
Synergistic Healing: HA Meets PRP
HyloPReP™ is a next-generation combination therapy that hydrates joints, supports cartilage healing, and improves mobility in patients with osteoarthritis of the knee. It Helps patients delay arthroplasty or overdependence on steriods.It delivers two biological benefits in one injection:
HyloPReP™ is a next-generation combination therapy that hydrates joints, supports cartilage healing, and improves mobility in patients with osteoarthritis of the knee. It Helps patients delay arthroplasty or overdependence on steriods.It delivers two biological benefits in one injection:
Hyaluronic Acid (HA)
Restores lubrication and viscoelasticity in the synovial joint.
Leukocyte-Poor PRP
Delivers concentrated growth factors minus WBCs to promote cartilage repair and reduce inflammation.
Synergistic Healing: HA Meets PRP
HyloPReP™ is a next-generation combination therapy that hydrates joints, supports cartilage healing, and improves mobility in patients with osteoarthritis of the knee. It Helps patients delay arthroplasty or overdependence on steriods.It delivers two biological benefits in one injection:
Hyaluronic Acid (HA)
Restores lubrication and viscoelasticity in the synovial joint.
Leukocyte-Poor PRP
Delivers concentrated growth factors minus WBCs to promote cartilage repair and reduce inflammation.
What makes HyloPReP™ unique?
Based On
Synergistic Lubricative Regenerative Technology joints
Effective
Lubricates & Preserves Joint System
Versatile
One-Step Holistic Approach for OA repair
Available in two versions for procedural flexibility
Available in two versions for procedural flexibility
HyloPReP™ S Kit:
HA (2 mL) + LP-PRP (4–5 mL) — 1 month shot × 2 sessions.
HyloPReP™ L Kit
HA (6 mL) + LP-PRP (4-5 mL) Single injection, 6–12-month interval.
HyloPReP™ S Kit:
HA (2 mL) + LP-PRP (4–5 mL) — 1 month shot × 2 sessions.
HyloPReP™ L Kit
HA (6 mL) + LP-PRP (4-5 mL) Single injection, 6–12-month interval.
Clinical Benefits – Backed by Science, Built for Relief
Clinical Benefits – Backed by Science, Built for Relief
Pain & Function: Clinical studies show combined HA + PRP injections outperform either alone in reducing pain and improving WOMAC & VAS scores for 6–12 months
Pain & Function: Clinical studies show combined HA + PRP injections outperform either alone in reducing pain and improving WOMAC & VAS scores for 6–12 months
Chondroprotective Action: Growth factors from LP-PRP upregulate collagen II and suppress MMPs, slowing OA progression
Chondroprotective Action: Growth factors from LP-PRP upregulate collagen II and suppress MMPs, slowing OA progression
At 6-month follow-up, the HA + PRP group demonstrated the greatest reduction in WOMAC and VAS scores, showing continuous improvement up to 6 months with no major complications
At 6-month follow-up, the HA + PRP group demonstrated the greatest reduction in WOMAC and VAS scores, showing continuous improvement up to 6 months with no major complications
A systematic review of 11 RCTs (n≈1023) confirmed that PRP + HA therapy is safe and provides superior pain relief and functional improvement compared to PRP alone, with a low adverse-event rate
A systematic review of 11 RCTs (n≈1023) confirmed that PRP + HA therapy is safe and provides superior pain relief and functional improvement compared to PRP alone, with a low adverse-event rate
What makes HyloPReP™ unique?
Based On
Synergistic Lubricative Regenerative Technology joints
Effective
Lubricates and Preserves Joint System
Versatile
One-Step Holistic Approach for OA repair
Comparative Edge - For Clinicians
Who Want Predictable Outcomes
Comparative Edge - For Clinicians
Who Want Predictable Outcomes
Feature / Benefit
HyloPReP™
Generic HA + PRP Injections
System Type
The total amount of cloud storage space allocated for your files.
Closed, sterile, ISO 13485
Open / mixed preparation
PRP Type
The speed at which you can upload and download files to and from the cloud.
LP-PRP (> 90 % WBC reduction)
Variable (often LR-PRP)
HA Quality
The largest file size you can upload in a single action.
European-grade, GMP verified
Generic
Dual Mechanism
The total amount of cloud storage space allocated for your files.
Lubrication + Regeneration
Lubrication only
Relief Duration
The speed at which you can upload and download files to and from the cloud.
6–12 months
2–4 months
Affordability
Manage access with a specified number of user accounts per plan.
Economical
Expensive
Potential Indications
Knee Osteoarthritis (Grade I–III)
Shoulder, Hip, and Ankle OA
Patients unfit or unwilling for surgery
Athletes / early OA cases seeking long-term mobility
Precision for Every Specialty
Knee Osteoarthritis (Grade I–III)
Athletes / early OA cases seeking long-term mobility
Patients unfit or unwilling for surgery
Shoulder, Hip, and Ankle OA
Answers to Common Questions
Answers to Common Questions
We’ve gathered the most frequently asked questions to help you better understand our AI services, pricing, and integration process.
We’ve gathered the most frequently asked questions to help you better understand our AI services, pricing, and integration process.
How does HyloPReP™ work to relieve OA symptoms and repair cartilage?
What’s the difference between HyloPReP™ S and L kits?
How soon do patients feel improvement?
Can HyloPReP™ be used in combination with PRP or BMAC?
How does HyloPReP™ compare in safety and cost?
What is Super-Dose PRP and why does it matter?
How many PRP sessions are needed for different conditions?
Why is Tubex® PRP superior to gel tubes or standard 10 mL PRP kits?
What are the main clinical indications for Tubex® PRP?
How does platelet dose affect outcomes?
Can Tubex® PRP prepare both LP-PRP and LR-PRP?
How consistent are Tubex® PRP results compared to other PRP kits?
Are there contraindications for PRP therapy?
Is PRP therapy safe?
How does vortex-based technology improve results?
How does PRP compare to steroids or surgery?
How does HyloPReP™ work to relieve OA symptoms and repair cartilage?
What’s the difference between HyloPReP™ S and L kits?
How soon do patients feel improvement?
Can HyloPReP™ be used in combination with PRP or BMAC?
How does HyloPReP™ compare in safety and cost?
References
References
1. Altman R.D. et al., Cartilage (2015): “Synergistic effects of HA + PRP in knee OA pain and function.”
2. Ozturk M. et al., J Orthop Surg Res (2018): “HA + PRP injections improve pain and WOMAC scores vs HA alone.”
3. Maheu E. et al., Rheumatology Int (2019): “Meta-analysis confirms additive benefits of PRP and HA in OA.”
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